Owen Farrell (concussion), Jonny May (elbow) and Henry Arundell (foot) have withdrawn from the England squad who will travel to Jersey today after sustaining injuries in their weekend games.
Tom Roebuck has been called up to the England squad for the first time. Adam Radwan and Henry Slade also make a return to the side.
Owen Farrell will progress through his graduated return to play protocols at home.
Henry Arundell will travel to Jersey for rehab, along with Will Stuart who is recovering from a knee injury.
Charlie Atkinson, who is currently unattached, will join up with the England squad as a training player.
England will spend five days in Jersey as they continue their preparations for their four Autumn Nations Series fixtures at Twickenham Stadium.
They will first take on Argentina, with limited tickets still available, on Sunday 6 November (2.15pm KO).
They will then host Japan (Saturday 12 November, 3.15pm KO) followed by New Zealand (Saturday 19 November 5.30pm) and South Africa (Saturday 26 November, 5.30pm KO).